Blogue dos Estudantes de Bioquímica da Universidade do Porto

11 Novembro 2008

Turn Plant Cells Into Medical Factories

The methods based on plant biotechnology are an alternative to chemical synthesis. By controlling the cell metabolism of a 'green factory', i.e. a living plant cell, it is possible to affect the production of desired high-value compounds. This kind of metabolic engineering also stimulates the cells towards producing completely new compounds.

Plants generate valuable secondary metabolic compounds, which can be used as pharmaceuticals. Most of these compounds are so complex that their chemical synthesis is not economically feasible. This is why biotechnology opens up a whole new avenue of possibilities. The SmartCell project will focus on terpene compounds, which are valuable for the pharmaceutical industry. These compounds for example are used in the treatment of cancer and malaria. The expertise and technology created during the project can be applied to a considerable extent in developing the biotechnological production of other compound groups in plants and plant cells.

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